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1-[2-(2-Thienylcarbonyl)ethyl]-4-[3-(trifluoromethyl)phenyl]piperazin-1-ium chloride

✍ Scribed by Chen, Xue-Jun ;Tan, Sheng ;Shang, Zhen-Hua ;Feng, Guang-Bin

Publisher: International Union of Crystallography
Year: 2007
Tongue: English
Weight: 612 KB
Volume: 63
Category: Article
ISSN: 1600-5368
DOI: 10.1107/s1600536807029522

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✦ Synopsis

The title compound, C 18 H 20 F 3 N 2 OS + ÁCl À , was synthesized from 2-acetothiophene, 1-[3-(trifluoromethyl)phenyl]piperazine and paraformaldehyde. There are two independent ion pairs in the asymmetric unit. In each cation, the piperazine ring adopts a chair conformation and the F atoms of the trifluoromethyl groups are disordered over two sites with a ratio of major and minor occupancy of approximately 0.6:0.4. Two intermolecular N-HÁ Á ÁCl hydrogen bonds help to stabilize the crystal structure.

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