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(09) Comparison of the potency of newly developed and currently available oximes to reactivate nerve agent-inhibited acetylcholinesterase in vitro and in vivo

✍ Scribed by Kamil Kuca; Lucie Bartosova; Jiri Kassa; Jiri Cabal; Jiri Bajgar; Gabriela Kunesova; Daniel Jun


Book ID
113517255
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
90 KB
Volume
157-158
Category
Article
ISSN
0009-2797

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Comparison of in vitro potency of oximes
✍ Kamil Kuca; Jiri Cabal; Jiri Kassa; Daniel Jun; Martina HrabinovΓ‘ πŸ“‚ Article πŸ“… 2005 πŸ› John Wiley and Sons 🌐 English βš– 150 KB

The potency of currently used oximes to reactivate sarin-inhibited acetylcholinesterase (AChE) in various parts of pig brain and whole pig brain was evaluated using in vitro methods. Significant differences in reactivation potency among all tested oximes were observed. At concentrations (10 - ----4