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052 Efficacy of anti-epileptic drugs in children with Angelman syndrome associated with 15Q11-13 deletion

✍ Scribed by T. Balslev; J.R. Østergaard


Book ID
114360942
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
130 KB
Volume
3
Category
Article
ISSN
1090-3798

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Deletion breakpoints associated with the
✍ Wendy P. Robinson; Roland Spiegel; Albert A. Schinzel 📂 Article 📅 1993 🏛 Springer 🌐 English ⚖ 372 KB

Deletions of 15q11.2-q12 are associated with either the Prader-Willi (PWS) or Angelman (AS) syndromes. It has been suggested that excessive recombination in this region might explain the high frequency of such deletions, and the frequent involvement of chromosome 15 in translocations and nondisjunct