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05 Titin isoform expression in normal and hypertensive rat myocardium

โœ Scribed by Chad M. Warren; Maria C. Jordan; Kenneth P. Roos; Marion L. Greaser

Book ID
117141731
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
134 KB
Volume
34
Category
Article
ISSN
0022-2828

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## Abstract Titin is a giant protein with multiple functions in cardiac and skeletal muscles. Rat cardiac titin undergoes developmental isoform transition from the neonatal 3.7โ€‰MDa N2BA isoform to primarily the adult 2.97โ€‰MDa N2B isoform. An autosomal dominant mutation dramatically altered this tra