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046 Regulation of matrix metalloproteinases (MMP) expression in cutis laxa fibroblasts: Upregulation of MMP-1, MMP-3 and MMP-9 genes but not of MMP-2 gene

✍ Scribed by Hatamochi, A.; Kuroda, K.; Shinkai, H.


Book ID
119174359
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
102 KB
Volume
12
Category
Article
ISSN
0923-1811

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A major histopathological abnormality in cutis laxa (CL) is a paucity of elastic structures. The aim of this study was to investigate the gene expression levels of the major matrix degrading factors matrix metalloproteinase (MMP) 1, MMP-2, MMP-3 and MMP-9 in CL. The gene expression levels of MMP-1,