Chloramphenicol-induced mitochondrial dy
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Lorene M. Leiter; Hemant S. Thatte; Chukwuka Okafor; Peter W. Marks; David E. Go
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Article
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1999
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John Wiley and Sons
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English
⚖ 347 KB
Chloramphenicol is an antibiotic that consistently suppresses the bone marrow and induces sideroblastic anemia. It is also a rare cause of aplastic anemia. These toxicities are thought to be related to mitochondrial dysfunction, since chloramphenicol inhibits mitochondrial protein synthesis. We hypo