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0230 Polymorphisms of the amyloid precursor protein (APP) gene in Chinese/Taiwanese patients with late-onset Alzheimer's disease (LOAD)


Book ID
119466779
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
125 KB
Volume
238
Category
Article
ISSN
0022-510X

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## Abstract Linkage studies have suggested a susceptibility locus for late‐onset Alzheimer's disease (LOAD) on chromosome 21. A functional candidate gene in this region is the β‐amyloid precursor protein (APP) gene. Previously, coding mutations in APP have been associated with early onset Alzheimer