016 Soluble c-KIT and soluble SCF in human serum
β Scribed by Kanbe, T.; Kawa, Y.; Kubota, Y.; Mizoguchi, M.; Yamada, H.
- Book ID
- 119174331
- Publisher
- Elsevier Science
- Year
- 1996
- Tongue
- English
- Weight
- 127 KB
- Volume
- 12
- Category
- Article
- ISSN
- 0923-1811
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## Abstract ## Background Although adenoviral vectors primarily derived from the adenovirus serotype 5 (Ad5) are widely used for many gene transfer applications, they cannot efficiently infect hematopoietic cells, since these cells do not express the coxsackieβadenoviral receptor (CAR). ## Method
We describe the first evidence that soluble asialoglycoprotein receptors (AGPR) are present in human serum and that they are quantifiable by an enzyme-linked immunosorbent assay (ELISA). An affinity chromatography gel immobilized with monoclonal antibodies (McAbs) against human liver AGPR was mixed